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Living Kidney Donor Annual Physical Examination.


Have a copy of the donation records sent to the primary care physician. Discuss the potential risks, complications and issues at the next appointment. Not all physicians are savvy in terms of single-kidneyed persons, especially living donors. It is possible the living donor will have more extensive knowledge.


Follow-up lab tests should include:

  • Urinalysis - macro, micro and culture. This detects and measures protein and potential bacteria in the urine.

  • Urine albumin: creatinine ratio - Excretion of even small amounts of albumin in the urine may portend serious future events, such as Chronic Kidney Disease and progressive renal dysfunction (95)  Albuminuria is the hallmark of hyperfiltration damage (173)

If a urine sample contains more than 30 milligrams of albumin for each gram of creatinine (30 mg/g), ask for a more detailed test. If the laboratory test exceeds 30 mg/g, another UACR test should be done 1 to 2 weeks later (221).


  • Microalbumin can be a precursor to protein in the urine (proteinuria). Protein are large molecules which can damage the kidney. Conversely, malfunctioning kidneys can themselves be the cause of the secreted protein.

According to the National Institutes of Health, a normal urine protein is < 80 mg per 24 hours.


  •  Serum creatinine or full basic metabolic profile - This evaluates the current status of the kidneys (including BUN/Blood Urea Nitrogen and Creatinine levels), electrolyte, blood sugar and calcium levels.

Normal Blood Creatinine (222):

Men: 0.6-1.2 milligrams per deciliter (mg/dL) or 71-106 micromoles per liter (mcmol/L)

Women: 0.4-1.0 mg/dL or 36-90 mcmol/L


Creatinine Clearance is determined by a 24-hour urine collection.

Men (younger than 40 years): 107-139 milliliters per minute (mL/min) or 1.8-2.3 milliliters per second (mL/sec)

Women (younger than 40 years): 87-107 mL/min or 1.5-1.8 mL/sec

Creatinine clearance values normally decrease with age, 6.5 mL/min every 10 years past the age of 20 (222)


BUN/Blood Urea Nitrogen to Creatinine ratio: 10:1 to 20:1


  • Fasting blood glucose or Hemoglobin A1C.


  • Lipid profile - in other words, watch your cholesterol!


  • CBC (Complete Blood Count) – Kidneys produce a hormone that signals the body to produce red blood cells. This test, among other things, will monitor for anemia.


If the 'estimated' GFR is below 60, request a true measured GFR through a 24-hour urine collection and concurrent blood draw for creatinine. A GFR below 60 is considered Stage 3 Chronic Kidney Disease.


  • Consider a bone density test.


Last Updated: November 30, 2012