Informed Consent Liver Donor Living Donor Research Psychosocial Risks

Complications and Quality of Life for Pediatric Live Liver Donors

Pediatric liver donors have the smaller lobe removed, as opposed to adult-to-adult living liver donation, which requires 60-75% of the donor’s liver. Pediatric liver donation has a lower surgical, or short-term, complication rate than adult-to-adult.


 A total of 13% of the donors developed postoperative complications of Clavien grades I (7%), II (3%), and IIIA (3%). There was no grade IV morbidity or mortality. 


…donors had difficulty in the decision-making process, and suggested that it may be necessary to administer multistep informed consent. We identified unique predictive risk factors for lower SF-36 scores in the donors, which were the time to donation (more than 4 weeks) and the predonation self-oriented perception. The donors who have risk factors require enhanced pre- and post-donation psychological care.


Unfortunately, like with most recently published articles, I am unable to access the full study without payment.

I’m curious to know what the researchers mean by “predonation self-oriented perception”. Are we talking about high expectations for transplant success? Or expectations regarding the relationship with the recipient? Or are the authors trying to say NARCISSIST nicely?

It’s also important to remember this are Japanese liver donors, so there may be some cultural differences.

Fukuda A, Sakamoto S, Shigeta T, Uchida H, Hamano I, Sasaki K, Kanazawa H, Loh DL, Kakee N, Nakazawa A, & Kasahara M (2014). Clinical Outcomes and Evaluation of the Quality of Life of Living Donors for Pediatric Liver Transplantation: A Single-Center Analysis of 100 Donors. Transplantation proceedings PMID: 24836837

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