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Living Donor Research

Could Kidney Graft Survival Be Genetics (in part)?

A study recently published in the American Journal of Transplantion reveals that kidneys from donors with two APOL1 genes (one from each parent) had significantly shorter graft survival than kidneys from donors with one copy of the gene, or none at all.

APOL1 is a gene usually found in African-Americans and is strongly associated with nephropathy (kidney disease). If this result can be duplicated and confirmed, testing for this gene could reduce the risks to potential living donors as well as improve quality transplants for recipients.

Press Release about aforementioned study.

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