A single center analysis of 77 living kidney donors 5 or more year post-donation has found that men and those with high BMI are at higher risk of low GFR (kidney function < 60), hypertension, and proteinuria; all symptoms of eventual kidney failure.
Unfortunately, I couldn’t access the complete article, so I don’t know if there’s a correlation between pre-donation levels and this post-donation result. However, it’s been previously established that folks with high BMI may already be hyperfiltrating pre-donation, which means their capacity for “compensation” post-donation is already maximized. So, this result just adds to that literature.
Bello, R., Bello, V., Rosa, T., Junqueira, L., Freitas, E., & Veiga, J. (2015). Male Gender and Body Mass Index Are Associated With Hypertension and Reduced Kidney Function 5 or More Years After Living Kidney Donation Transplantation Proceedings, 47 (10), 2816-2821 DOI: 10.1016/j.transproceed.2015.10.041