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Risks of Being Born With Solitary Kidney

When the long-term risks of donating a kidney are discussed, too often someone will bring up that folks born with one kidney are ‘fine’. So I wanted to share this:

 

Children with a solitary kidney (SK) have an increased long-term risk of hypertension, albuminuria and glomerulosclerosis.

 

A two-kidneyed person relinquishing a kidney is not different, in terms of these risks. That’s because renal reserve, nephron count and kidney function plays a role in those above factors. The problem is that potential living kidney donors aren’t educated about what kidneys actually *do* or what the affect will be when one is removed.

Emphasis mine:

Among our patient cohort, renal function was well preserved at ages 4–15.5 years in children who were born with a SK [solitary kidney]. However, both their higher blood pressure and RI [resistance index of arteries. This refers to arterial hardening] and the correlation of 24-h albumin urinary excretion with length of follow-up time underline the need for monitoring to detect early signs of glomerular hyperfiltration and, if necessary, implement timely intervention. SK hypertrophy was found to be correlated with postnatal growth.

 

 

http://link.springer.com/article/10.1007/s00467-013-2623-4

 
Ekaterini Siomou, Vasileios Giapros, Frederica Papadopoulou, Maria Pavlou, Andreas Fotopoulos, Antigoni Siamopoulou (2013). Growth and function in childhood of a normal solitary kidney from birth or from early infancy Pediatric Nephrology DOI: 10.1007/s00467-013-2623-4

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