Living Donor Risks

Losing a Whole Kidney vs. Part of One Matters

I’ll let the authors begin:


 It is clear  that Chronic Kidney Disease  (GFR <60mls/min) is associated with reduced  life  expectancy,  partly  due  to  an  increased  risk  of  cardiovascular  disease.


Are we clear? Reduced kidney function = increased risk of cardiovascular disease. Try to remember that when a member of the transplant industry tries to say that living kidney donors have no increased risk of heart disease.


Anyway, so these authors compared two groups: those who had a whole kidney removed, and those who only had part of a kidney removed.


16.7& of those who had a partial nephrectomy had a post-surgical GFR <60.

35.4% of the full nephrectomy group had GFR of <60.

Six months post-nephrectomy. (PS. GFR <60 is considered Stage 3 Chronic Kidney Disease.)


Their conclusion:


Smaller  reductions  of  GFR  after  partial  versus  total  unilateral nephrectomy  are  of  magnitudes  that  are  significant  for  overall  life  expectancy  in  large  cohorts



Stephen  KD  Hamilton , Grant  D  Stewart , Alan  McNeill , Antony CP  Riddick   , & Richard  Phelps  (2014). Renal Function After Unilateral Nephrectomy
Scottish Universities Medical Journal  , 3 (2), 22-31